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close this bookGuidelines for the Treatment of Malaria (WHO; 2006; 266 pages) View the PDF document
View the documentGlossary
View the documentAbbreviations
close this folder1. Introduction
View the document1.1 Background
View the document1.2 Objectives and target audience
View the document1.3 Methods used in developing the guidelines and recommendations
View the document2. The clinical disease
open this folder and view contents3. Treatment objectives
open this folder and view contents4. Diagnosis of malaria
open this folder and view contents5. Resistance to antimalarial medicines9
open this folder and view contents6. Antimalarial treatment policy
open this folder and view contents7. Treatment of uncomplicated P. Falciparum malaria10
open this folder and view contents8. Treatment of severe falciparum malaria14
open this folder and view contents9. Treatment of malaria caused by P. vivax, P. ovale or P. malariae19
View the document10. Mixed malaria infections
open this folder and view contents11. Complex emergencies and epidemics
open this folder and view contentsAnnexes

1.2 Objectives and target audience

1.2.1 Objectives

The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of:

• uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV-positive, travellers from non-malaria endemic regions) and in epidemics and complex emergency situations;

• severe malaria.

The guidelines do not deal with preventive uses of antimalarials, such as intermittent preventive treatment or chemoprophylaxis.

1.2.2 Target audience

The guidelines are aimed primarily at policy-makers in ministries of health. The following groups should also find them useful:

• public health and policy specialists working in hospitals, ministries, nongovernmental organizations and primary health care services;

• health professionals (doctors, nurses and paramedical officers).

The guidelines provide a framework for the development of specific and more detailed treatment protocols that take into account national and local malaria drug resistance patterns and health service capacity (see Annex 2). They are not intended to provide a comprehensive clinical management guide for the treatment of malaria. However, where there are controversies about specific clinical practices, and evidence is currently available to provide information to guide decision-making about these practices, that information has been included.

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