The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of:
• uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV-positive, travellers from non-malaria endemic regions) and in epidemics and complex emergency situations;
• severe malaria.
The guidelines do not deal with preventive uses of antimalarials, such as intermittent preventive treatment or chemoprophylaxis.
1.2.2 Target audience
The guidelines are aimed primarily at policy-makers in ministries of health. The following groups should also find them useful:
• public health and policy specialists working in hospitals, ministries, nongovernmental organizations and primary health care services;
• health professionals (doctors, nurses and paramedical officers).
The guidelines provide a framework for the development of specific and more detailed treatment protocols that take into account national and local malaria drug resistance patterns and health service capacity (see Annex 2). They are not intended to provide a comprehensive clinical management guide for the treatment of malaria. However, where there are controversies about specific clinical practices, and evidence is currently available to provide information to guide decision-making about these practices, that information has been included.